Scientific Programme
last update: 2018-09-18
Tuesday, 18th September 2018 |
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15.00-17.30 | Meeting of the Board of Polish Biochemical Society Place: D209 |
18.00-19.30 | Opening ceremony Opening Lectures Place: S204/205 |
18.30-19.00 | PL.1. Ted Hupp University of Edinburgh, Scotland, International Centre for Cancer Vaccine Science Gdańsk Interferon responsive genes that link adaptive and innate immunity in human cancer Place: S204/205 |
19.00-19.30 | PL.2. Robin Fahraeus Paris Diderot University, France, International Centre for Cancer Vaccine Science Gdańsk Viral mRNA translation control: linking immune evasion with oncogenesis Place: S204/205 |
19.30 | Welcome Party Place: Upper level of the Faculty of Social Sciences University of Gdańsk |
Wednesday, 19th September 2018 |
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| Plenary Lecture | |||||
| Morning sessions 9.00-9.45 | PL.3. Marek Figlerowicz Institute of Bioorganic Chemistry PAS, Poznań, Poland Genomics in uncovering our history Place: S205 |
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| Session line | |||||
DNA World | RNA World | EMBO | Polish Society for Cell Biology |
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| session 1 Place: S204 | session 2 Place: S205 | session 3 Place: S207 | session 4 Place: S208 |
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| Morning sessions 9.45-13.15 | Marek Figlerowicz IBCh PAS, Poland Tomasz Żemojtel Berlin Inst. of Health, Germany Genomics and genomics-driven research | Andrzej Dziembowski IBB & UW, Poland RNA and RNP structures and mechanisms of action: from theory to experiment | Krzysztof Liberek IFB UG&MUG, Gdańsk, Poland Joanna Sułkowska CENT Poland EMBO Session | Halina Gabryś UJ, Cracow, Poland Signaling in plant cells |
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| Lectures: | Lectures: | Lectures: | Lectures: | ||
09.45-09.50 | IBCh PAS, Poland Tomasz Żemojtel Berlin Inst. of Health, Germany Short introduction | L.2.1. Marcin Nowotny IIMCB, Warsaw, Poland Structural and biochemical studies of the yeast mitochondrial RNA degradosome | Krzysztof Liberek IFB UG&MUG, Gdańsk, Poland Introduction | L.4.1. Ute Vothknecht Univ. of Bonn, Germany Calcium Regulation of Plant Organellar Metabolism |
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09.50-10.00 | L.3.1. Magda Konarska CENT, Warsaw, Poland, new EMBO member Dynamic rearrangements of the spliceosomal catalytic center |
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10.00-10.15 | L.1.1. Izabela Makałowska UAM, Poznań, Poland Activity of retroposed genes in tumors |
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10.15-10.30 | L.2.2. Jacek Jemielity CENT, Warsaw, Poland Chemically modified mRNA | L.3.2. Joanna Sułkowska CENTR, Warsaw, Poland EMBO Young Investigator Mysteries of entanglement – from a single protein to a pair of chromosomes | L.4.2. Axel Mithofer Max-Planck-Inst. for Chemical Ecology, Jena, Germany Plant Calcium Signaling in biotic Interactions |
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10.30-10.35 |
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10.35-10.40 | L.1.2. Tomasz Żemojtel Berlin Inst. of Health, Germany Liquid biopsy: challanges and opportunities |
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10.40-10.45 | L.3.3. Piotr Ziółkowski UAM, Poznań, Poland EMBO Installation Ggrantee Control of meiotic recombination: from chromosomal distribution to crossover frequency |
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10.45-11.05 | L.2.3. Maciej Kozak UAM, Poznań, Poland Applications of small-angle X-ray and neutron scattering (SAXS/SANS) in studies of complexes and flexible protein structures | L.4.3. Halina Gabryś UJ, Cracow, Poland Calcium and magnesium in blue light signaling in the mesophyll cell |
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11.05-11.10 | Break | ||||
11.10-11.15 | Break | ||||
11.15-11.35 | Break | ||||
11.35-11.40 | Break | L.3.4. Marta Miączyńska IIMCB, Warsaw, Poland new EMBO member Inflammatory signaling from the endocytic pathway | Break | ||
11.40-11.45 | L.1.3. Agnieszka Żmieńko AthCNV - a map of DNA copy number variations in Arabidopsis thaliana genome based on the 1001 Genomes Project data | Break | |||
11.45-12.00 | L.2.4. Krzysztof Ginalski CENT, Warsaw, Poland Identification and classification of proteins involved in nucleic acids metabolism | L.4.4. Dorota Konopka-Postupolska IBB, Warsaw, Poland The role of calcium in cellular membrane flow |
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12.00-12.15 | L.3.5. Maria Górna UW, Warsaw, Poland EMBO Installation Grantee Installation Grantee How to end a viral RNA- lessons from the IFIT proteins |
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12.15-12.25 | O.1.1. Małgorzata Marcinkowska-Swojak Half the costs keep the quality. Targeted enrichment for the Next Generation Sequencing of ancient genomes | L.2.5. Andrzej Dziembowski CENTIBB & UW, Warsaw, Poland Regulation of gene expression by non-canonical poly(A) and poly(U) polymerases | O.4.1.Małgorzata Pietrowska-Borek Is RAB GTPase homolog E1B (RABE1b) involved in response to cadmium stress in Arabidopsis thaliana seedlings by cGMP synthesis? |
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12.25-12.30 | L.3.6. Wojciech Pokrzywa IIMCB, Warsaw, Poland EMBO Installation grantee Chaperone-directed ubiquitylation maintains proteostasis at the expense of longevity |
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12.30-12.45 | O.1.2. Patrycja Jakubek Catechins as modulators of DNA methylation | O.4.2. Weronika Krzeszowiec-Jeleń Exogenous amino acids affect the image of actin cytoskeleton in Arabidopsis mesophyll cells |
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12.45-12.50 | O.1.3. Sabina Żołędowska Investigating the pangenome of the plant pathogenic Pectobacterium parmentieri provides insight into its outstanding adaptation abilities | O.2.1. Roman Szczęsny The mitochondrial degradosome complex and its co-factors prevent accumulation of double-stranded RNA in humans | |||
12.50-13.00 | L.3.7. Agata L. Starosta Undercover translation. Hidden secrets of the ribosome |
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13.00-13.15 | O.1.4. Agata Motyka Closure of the Dickeya solani pangenome | O.2.2. Michał Wojciech Szcześniak Long non-coding RNAs as modulators of splicing in trans via direct RNA:RNA interactions |
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13.30-14.15 | Lunch andPoster session: P1-P8 Poster sessions list |
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14.30-15.15 | PL.4. Bożena Kamińska-Kaczmarek Nencki Institute of Experimental Biology Polish Academy of Sciences, Warsaw, Poland Immune microenvironment of glioma Lecture sponsored by Nencki Inst. of Experimental Biology PAS, Warsaw, Poland- 100 years anniversary of the Nencki Inst. of Experimental Biology PAS Place: S205 |
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New molecular targets / World of application | RNA World | Protein World | Session sponsored by COST Action CA16112 "NutRedOx" |
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| session 5 Place: S204 | session 6 Place: S205 | session 7 Place: S207 | session 8 Place: S208 | session 30 Place: S211 |
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| Afternoon sessions 15.15-16.45 | Krystyna Bieńkowska-Szewczyk IFB UG&MUG, Gdańsk, Poland Bogusław Szewczyk UG&MUG Molecular virology | Zofia Szweykowska-Kulińska UAM, Poznań, Poland Piotr Kozłowski IBCh PAS, Poznań, Poland Non-coding RNA and gene expression | Marcin Nowotny IIMCB, Warsaw, Poland Alessandro Costa The Francis Crick Inst., London, UK Structural studies of large assemblie | Adam Szewczyk Nencki Inst. of Experimental Biology PAS, Warsaw, Poland Wiesława Jarmuszkiewicz UAM, Poznań, Poland Molecular bioenergetics | Caroline Gaucher University of Lorraine, Nancy, France Jędrzej Antosiewicz MUG, Gdańsk, Poland Redox control of major age-related diseases |
| Lectures: | Lectures: | Lectures: | Lectures: | Lectures: | |
15.15-15.25 | L.5.1. Timm C. Harder FLI, Riems, Germany 100 years from Spanish flu- can we control influenza today? | Zofia Szweykowska-Kulińska UAM, Poznań, Poland Piotr Kozłowski IBCh PAS, Poznań, Poland Marek Figlerowicz Institute of Bioorganic Chemistry PAS, Poznań, Poland Introduction In memory of Professor Włodzimierz Krzyżosiak | L.7.1. Wojciech Galej EMBL, Grenoble, France Structure and dynamics of the spliceosome | L.8.1. Wiesława Jarmuszkiewicz UAM, Poland Impact of temperature and training on skeletal muscle bioenergetics | L.30.1. Marc Diederich Seoul National University, Korea About canonical and less canonical cell death induction by natural compounds with pharmacological potential |
15.25-15.45 | L.6.1. Zofia Szweykowska-Kulińska UAM, Poland Biogenesis and function of plant microRNAs |
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15.45-16.05 | L.5.2. Arvind H. Patel MRC-University of Glasgow Centre for Virus Research, UK Conformational flexibility in the receptor-binding site of the Hepatitis C Virus Glycoprotein E2 100 years from Spanish flu- can we control influenza today? | L.6.2. Piotr Kozłowski IBCh PAS, Poznań, Poland Copy number variation and other types of genetic alterations in miRNA genes and their potential implications for miRNA function and human diseases | L.7.2. Alessandro Costa The Francis Crick Institute, London, UK Eukaryotic replisome assembly and fork progression visualized by cryo-EM | L.8.2. Wiesław Gruszecki UMCS, Lublin, Poland Warming-up of the chloroplast | L.30.2. Marek Naruszewicz Medical University of Warsaw, Poland Oleacein, translation from Mediterranean diet to preventive medicine |
16.05-16.15 | O.6.1. Susheel Sagar Bhat Arabidopsis thaliana mRNA adenosine methylase (MTA) is an important player in miRNA biogenesis regulatory pathway |
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16.15-16.25 | L.5.3. Alicja Chmielewska Adenovirus vectors for genetic vaccination and oncolytic virotherapy | O.6.2. Anna Kurzyńska-Kokorniak A possible direct involvement of Dicer ribonuclease in the post-transcriptional control of gene expression | L.7.3.Michał Szymański IFB UG & GUMed, Gdańsk, Poland Structure and function of macromolecular machines | L.8.3. Adam Szewczyk Nencki Inst. of Experimental Biology PAS, Warsaw, Poland Mitochondrial regulation of mitochondrial potassium channels | L.30.3. Tomris Ozben Natural redox modulators of oxidative stress and chemoresistance in cancer therapy: beneficial versus deleterious effects |
16.25-16.35 | O.6.3. Joanna Boguslawska TGF-β1 affects proliferation, viability and migration of renal cancer cells, possibly by targeting regulatory microRNAs |
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16.35-16.45 | O.6.4. Ankur Gadgil U7 snRNA activity and histone gene expression is affected by ALS-linked FUS mutations |
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16.45-17.00 | Break | Break | |||
17.00-18.00 | Sponsored session Place: S205 | O.8.1. Bogusz Kulawiak Single-channel properties of the ROMK2-pore-forming subunit of the mitochondrial ATP-regulated potassium channel |
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17.00-17.15 | Merck sponsored session Immunophenotyping Extracellular Vesicles using innovative flow cytometry |
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17.15-17.30 | O.7.1. Michał Gabruk Towards the near-atomic resolution structure of light-dependent protochlorophyllide oxidoreductase | O.8.2. Andonis Karachitos Evaluation of mitochondrial energetic status and oxidative stress during tardigrade anhydrobiosis |
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17.30-17.45 | O.8.3. Karol Parchem Dietary oxidized phospholipids: digestion, absorption and metabolism |
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17.45-17.55 | O.8.4. Karolina Dominiak Coenzyme Q and ROS production in mitochondria |
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17.55-18.00 |
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18.00-19.30 | General assembly of the Polish Biochemical Society Place: S205 |
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Thursday, 20th September 2018 |
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| Plenary Lecture | |||||
| Morning session 9.00-9.45 | PL.5. Peter Mackenzie Flinders University, Adelaide, Australia The UDP glycosyltransferase superfamily: its role in signal transduction termination and protection against chemical toxicity Lecture sponsored by the Rector of the Gdańsk University of Technology Place: S205 |
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Metabolite World | Cell & Organ World | DNA World | Sesion sponsored by COST Action CA16112 "NutRedOx" |
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9.45-11.15 | session 9 Place: S204 | session 10 Place: S205 | session 11 - part I Place: S207 | session 12 Place: S208 | session 30 part II Place: S211 |
Władysława A. Daniel PAS, Poland Krzysztof Safranow PUM, Szczecin, Poland The physiological and pharmacological regulation of endobiotic and drug metabolizing enzymes | Ryszard T. Smoleński MUG, Gdańsk, Poland Stefan Chłopicki UJ, Cracow, Poland Endothelial dysfunction and atherosclerosis | Agnieszka Łoboda UJ, Cracow, Poland Robert Passier University of Twente, Enschede, The Netherlands Medical biotechnology in regenerative medicine and drug research Session sponsored by STARBIOS 2 Structural Transformation to Attain Responsible BIOSciences EU FP Horizon 2020 | Jarosław Marszałek IFB UG&MUG, Gdańsk, Poland Ryszard Korona UJ, Cracow, Poland Evolutionary biochemistry | Agnieszka Bartoszek Gdańsk University of Technology, Gdańsk Mustafa C. Malki Université de Bourgogne, Dijon, France Redox control of major age-related diseases |
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09.45-10.15 | L.9.1. Władysława A. Daniel PAS, Poland The regulation of liver cytochrome P450 by the brain nervous system | L.10.1. Ryszard T. Smoleński MUG, Gdańsk, Poland Energetics of cardiac myocyte in atherosclerosis | L.11.1. Graziella Pellegrini Univ. of Modena, Italy Epithelial stem cells, a real tool for effective regenerative medicine treatments | L.12.1. Grzegorz Kudła Univ. of Edinburgh, UK Next generation genotype-phenotype mapping | L.30.4. Linda Giblin Whey Protein: can it boost cellular antioxidant processes? |
10.15-10.45 | L.9.2. Krzysztof Safranow PUM, Szczecin, Poland Consequences of muscle AMP deaminase deficiency caused by common nonsense mutation In AMPD1 gene – a new look at the role of purine nucleotide cycle | L.10.2. Stefan Chłopicki UJ, Cracow, Poland Endothelial profiling in vivo: novel approach to experimental pharmacology of endothelium | L.11.2. Józef Dulak UJ, Cracow, Poland Targeting inflammation for treatment of Duchenne muscular dystrophy | L.12.2. Kataryna Tomala UJ, Cracow, Poland Searching for factors underlaying slower evolution of abundant proteins | L.30.5. Jarosław Paluszczak Modulation of Wnt signaling by natural and synthetic compounds in cancer cells |
10.45-11.00 | O.9.1. Agnieszka Potęga Electrochemistry/liquid chromatography/mass spectrometry for the simulation of in vitro metabolism of unsymmetrical bis-acridines with antitumor properties | O.10.1. Alicja Bulińska Nucleotide and adenosine converting ecto-enzyme pattern in endothelial activation and vascular inflammation | O.11.1. Krzysztof Kobielak Regulation of hair follicle stem cells homeostasis by activation of gene inhibitory network | L.12.3. Ryszard Korona UJ, Cracow, Poland The paradox of dominance: halving the dose of a gene leaves its function unaffected (usually) | |
11.00-11.15 | O.10.2. Armen Trchounian Antioxidant activity of alcohol extracts from some plants of Armenian flora: the highest level and its possible nature | O.11.2. Jacek Stępniewski Administration of HO-1/SDF-1α-overexpressing mesenchymal stromal cells in murine and swine model of myocardial infarction and heart failure – analysis of therapeutic effect |
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11.15-11.45 | Break | ||||
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Metabolite World | Cell & Organ World | New molecular targets / World of application |
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11.45-13.15 | session 13 Place: S204 | session 14 Place: S205 | session 11 - part II Place: S207 | session 15 Place: S208 |
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Wanda Baer-Dubowska PUMS, Poland Gniewomir Latacz UJ, Cracow, Poland Metabolic activation of xenobiotics - therapeutic target and drug monitoring | Anna Ronowska Medical University of Gdańsk, Poland Andrzej Szutowicz Medical University of Gdańsk, Poland New biomarkers in neurodegenerative diseases | Józef Dulak UJ, Cracow, Poland Graziella Pellegrini University of Modena, Modena, Italy Medical biotechnology in regenerative medicine and drug research Session sponsored by STARBIOS 2 Structural Transformation to Attain Responsible BIOSciences EU FP Horizon 2020 | Tomasz Wilanowski Nencki Inst. of Experimental Biology PAS, Warsaw, Poland Anna Radominska-Pandya University of Arkansas of Medical Sciences , USA New molecular targets in personalized therapy of cancer |
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| Lectures: | Lectures: | Lectures: | Lectures: | ||
11.45-12.15 | L.13.1. Uwe Sauer Inst. of Molecular Systems Biology, Switzerland Metabolic coordination through metabolite-protein interactions | L14.1. Monika Szeliga-Mossakowski Medical Research Centre PAS, Warsaw, Poland Astroglia in health and pathology | L.11.3. Robert Passier Univ. of Twente, The Netherlands Human pluripotent stem cell-derived cardiac cells for disease modeling, drug screening and regenerative medicine | L.15.1. Tomas Wilanowski Nencki Inst. of Experimental Biology PAS, Warsaw, Poland Grainyhead-like transcription factors as targets of anti-cancer therapy |
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12.15-12.45 | L.13.2. Hanna Piotrowska-Kempisty PUMS, Poland The metabolic activation of methylated resveratrol analogue 3,4,4’,5-tetra-methoxystilbene (DMU-212) to 3’hydroxy-3,4,4,4’-tetramethoxystilbene (DMU-214) | L.14.2. Andrzej Szutowicz MUG, Gdańsk, Poland Regulatory effects of acetyl-CoA distribution in cellular compartments of healthy and diseased brain | L.11.4. Agnieszka Łoboda UJ, Cracow, Poland HO-1 as a possible drug target | L.15.2. Anna Radominska-Pandya UAMS, USA Natural Compounds Activating Cannabinoid Receptors CB1 and CB2: future for the cancer treatments |
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12.45-12.55 | O.13.1. Mikhail Kurbat Hyperhomocysteinemia caused by highly active antiretroviral therapy (HAART) of HIV infection: focus on mitochondria | O.14.1. Anna Ronowska Thiamine deficits aggravate zinc cytotoxicity in cholinergic SN56 neuronal cells | O.11.3. Katarzyna Kaławaj Alpha-ketoglutarate (AKG) induces apoptosis in osteosarcoma cells in vitro through the activation of JNK MAP kinase | O.15.1. Małgorzata Rogalińska The importance of drug type and dose on CLL cells in vitro sensitivity to anticancer-agents |
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12.55-13.00 | O.15.2. Łukasz Skalniak Novel strategies of PD-1/PD-L1 immune checkpoint blockade for cancer therapy: antibodies, peptides and small molecule |
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13.00-13.05 | O.13.2. Annamaria Lubelska Metabolic stability as a challenge in the early stage of drug discovery process – in vitro determination of metabolic pathways for new promising 5-HT7R ligands | O.11.4. Izabela Sadowska-Bartosz 3-Bromopyruvic acid: a small molecule with strong anti-tumor potency |
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13.05-13.15 | O.15.3. Błażej Rubiś Telomerase targeting modulates cancer response to therapy |
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13.30-14.15 | Lunch andPoster session: P11-P19 Poster sessions list |
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14.30-15.15 | PL.6. Narayanan Veeraraghavan Rady Children’s Hospital-San Diego, USA Clinical Utility of Rapid Whole Genome Sequencing in pediatric critical care Lecture sponsored by Rector of the Medical University of Gdańsk Place: S205 |
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Metabolite World | Cell & Organ World | New molecular targets / World of application | Satellite session: Women in Science |
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15.15-16.45 | session 16 Place: S204 | session 17 Place: S205 | session 18 Place: S207 | session 19 Place: S208 | Satellite session 1 Place: S211 |
Micał Markuszewski MUG, Gdańsk, Poland Micał Ciborowski Medical University of Bialystok Clinical metabolomics | Rafał Sądej IFB UG&MUG, Poland Anna Żaczek IFB UG&MUG, Poland Tumor microenvironment in cancer progression | Piotr Trzonkowski MUG, Poland Ewa M. Martinez-Caceres Generalitat de Catalunya, Spain New molecular targets in personalized therapy of autoimmune diseases Session sponsoring by - COST project - Action to Focus and Accelerate Cell-based Tolerance-inducing Therapies BM1305, EU FP Horizon 2020. | Hanna Jańska UWr, Wrocław, Poland Agnieszka Mostowska UW, Warsaw, Poland Inside plant organelles: structure, function and stress response | Session sponsored by L’Oreal Poland Chairwoman - Agnieszka Chacińska Centre of New Technologies University of Warsaw, Poland |
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| Lectures: | Lectures: | Lectures: | Lectures: | Lectures: | |
15.15-15.45 | L.16.1. Danuta Dudzik San Pablo CEU University, Madrid, Spain Metabolomics meets clinics - application to maternal-fetal and neonatal medicine | L.17.1. Przemysław Juszczyński IHiTM, Poland Tumor suppressor function of FOXO1 in diffuse large B-cell lymphomas: mechanisms of regulation and rational targeting strategies Parnas Memory Lecture | L.18.1. Ewa M. Martinez-Caceres Generalitat de Catalunya, Spain Tolerance-induction with autologous tolerogenic dendritic cells treated with VITamin D3 and loaded with myelin peptides in MultiPe Sclerosis (Tolervit-MS) | L.19.1. Oliver van Aken Lund Univ., Sweden Exploring organelle-to-nuclear signaling during plant stress responses. | Annie Black Deputy Executive Director L'Oréal Corporate Foundation, France Introduction Agnieszka Chacińska Centre of New Technologies University of Warsaw, Poland Panelists: Bożena Kamińska Nencki Institute of Experimental Biology Polish Academy of Sciences, Warsaw, Poland Agata Starosta Maria Curie Skłodowska University in Lublin, Poland Joanna Sułkowska Centre of New Technologies University of Warsaw, Poland Zofia Szweykowska-Kulińska Adam Mickiewicz University Poznań, Poland |
15.45-16.15 | L.16.2. Michał Ciborowski Medical University of Bialystok, Poland Metabolomics in the clinical settings. Applications in diabetology and endocrinology | L.17.2. Katarzyna Miękus UJ, Cracow, Poland Role of anti-inflammatory protein MCPIP1 in clear cell renal cell carcinoma progression | L.18.2. Piotr Trzonkowski MUG, Gdańsk, Poland T-regulatory cells to treat autoimmune diseases | L.19.2. Łucja Kowalewska UW, Warsaw, Poland Structural plasticity of the chloroplast thylakoid network. |
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16.15-16.45 | L.17.3. Rafał Sądej IFB UG&MUG, Gdańsk, Poland Tumour microenvironment in luminal breast cancer progression | L.19.3. Małgorzata Heidorn-Czarna UW, Warsaw, Poland Functional relevance of mitoproteases in plant mitochondria. |
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16.45-17.00 | Break | ||||
17.00-18.30 | session 20 Place: S204 | session 17 continued Place: S205 | session 21 Place: S207 | session 22 Place: S208 |
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Ewa Świeżewska IBB, Warsaw, Poland Anna Ihnatowicz IFB UG&MUG, Gdańsk, Poland Plant biochemistry and metabolomics | Rafał Sądej IFB UG&MUG, Poland Anna Żaczek IFB UG&MUG, Poland Tumor microenvironment in cancer progression | Marta Olejniczak IBCh PAS, Poznań, Poland Krzysztof Chyliński CRISPR Lab, Wien, Austria CRISPR technologies for targeted genome editing | Dariusz Rakus UWr, Wrocław, Poland Jacek R. Wiśniewski MPI Biochemie, Germany Proteomics of ageing and diseases |
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| Lectures: | Oral presentations | Lectures: | Lectures: | ||
17.00-17.20 | L.20.1. Asaph Aharoni Weizmann Inst., Israel Plant ‘Metabolic Caravans’: from anti-nutritional to anti-Parkinson alkaloids | O.17.1. Halina Waś Chemotherapeutics-treated cancer cells display stem-like and senescent cell feature | L.21.1. Krzysztof Chyliński CRISPR Lab Vienna, Austria Temporal control of CRISPR/Cas9 activity | L.22.1. Jacek R. Wiśniewski MPI Biochemie, Germany Large scale proteomics for studying physiology and disease |
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17.20-17.30 | |||||
17.30-17.40 | L.20.2. Anna Ihnatowicz IFB UG&MUG, Gdańsk, Poland Genetic regulation of isoprenoid accumulation in plants – what have we learned from analysis of biochemical and genetic data? | L.21.2. Marta Olejniczak IBCh PAS, Poznań, Poland Evaluation of CRISPR/Cas9-mediated genome editing efficiency | L.22.2. Aneta Stachowicz Proteomics of plasma fibrin clot in antiphospholipid syndrome |
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17.40-17.55 | O.17.2. Natalia Bednarz-Knoll Preoperative high platelets counts and low hemoglobin correlate to mesenchymal phenotype of circulating tumor cells and worse clinical outcome in human breast carcinoma |
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17.55-18.00 | O.17.3. Aleksandra Solecka The influence of metabolism on the phenotype of astrocytoma U-251 MG cell line |
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18.00-18.10 | O.20.1. Joanna Grzyb Bionanohybrids between phycobilisomes and colloidal quantum dots – studies of energy transfer in complicated systems | L.22.3. Dariusz Rakus UWr, Wrocław, PolandAging-associated changes in hippocampal glycogen metabolism. Evidence for and against astrocyte-neuron lactate shuttle |
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18.10-18.15 | O.17.4. Izabela Papiewska-Pająk Extracellular vesicles secreted by colorectal cancer cell line HT29 overexpressing Snail can fuse with and activate the cells constituting metastatic niche |
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18.15-18.25 | O.20.2. Katarzyna Jasieniecka-Gazarkiewicz Acyl-CoA:lysophosphatidylethanolamine acyltransferase (LPEAT) activity regulates plant growth and autophagy level |
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18.25-18.30 | O.17.5. Magdalena Mizerska-Kowalska Tumor-associated neutral endopeptidase (tNEP) regulates cell proliferation and TGF-β production in cultures and co-cultures of colon cancer cells with colon fibroblasts |
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18.30-18.40 | |||||
20.00 | Gala Dinner including complimentary lecture Place: UNICORN Restaurant |
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Friday, 21st September 2018 |
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| Plenary lecture | ||||
9.00-9.45 | PL.7. Magdalena Król SGGW, Warsaw, Poland The macrophage-drug conjugate (MDC) as a „Trojan horse” approach in cancer therapy Polish Biochemical Society & L’Oreal for Women in Science Honorary Lecture Place: S205 |
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Metabolite World | Cell & Organ World | World of Application / Bioinformatics |
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9.45-11.15 | session 23 Place: S204 | session 24 Place: S205 | session 25 Place: S207 |
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Joanna Sułkowska CENT, Warsaw, Poland Andrzej Joachimiak Argonne National Laboratory, Argonne, USA Entanglement in biology - from proteins folding to drug design | Grzegorz Węgrzyn UG, Gdańsk, Poland Ewa Bartnik UW, Warsaw, Poland Mitochondrial and lysosomal diseases | Cezary Czaplewski UG, Gdańsk, Poland Stanisław Ołdziej IFB UG&MUG, Gdańsk, Poland From experimental data to in silico simulations and way back Session sponsored by Openexome |
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| Lectures: | Lectures: | Lectures: | ||
9.45-10.15 | L.23.1. Andrzej Joachimiak Argonne National Laboratory, Argonne, USA Targeting allosteric site in drug discovery – a case of tryptophan synthase | L.24.1. Grzegorz Węgrzyn UG, Gdańsk, Poland Mechanisms and therapeutic options of lysosomal storage diseases | L.25.1. Pavel Jungwirth Inst. Organic Chemistry and Biochemistry, ASCz, Prague, Czech Rep. Cell Penetration and Membrane Fusion: Two Sides of the Same Coin Lecture Sponsored by the Rector of the University of Gdańsk |
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10.15-10.45 | L.23.2. Ya-Ming Hou Thomas Jefferson University, Philadelphia, USA tRNA methylation: a determinant of mitochondrial pathogenesis | L.24.2. Ewa Bartnik UW, Wrocław, Poland Leber's hereditary optic neuropathy | L.25.2. Cezary Czaplewski UG, Gdańsk, Poland Modeling of protein structure and dynamics with the UNRES force field assisted by limited experimental data and knowledge-based information |
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10.45-11.00 | O.23.1. Rafal Augustyniak Visualizing supramolecular machines in action by methyl TROSY-NMR - substrate processing by AAA+ unfoldases | O.24.1. Katarzyna Tońska Nuclear genes involved in mitochondrial diseases with mitochondrial DNA instability in adults | O.25.1. Piotr Setny Protein hydraulics: water driven substrate binding cooperativity to protein kinase A |
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11.00-11.15 | O.23.2. Agata Perlinska Characterization of substrate binding and function of a knotted protein | O.24.2. Marta Kaczor-Kamińska The murine cellular model of mucopolysaccharidosis III, type B (MPS IIIB) – a preliminary study | O.25.2. Stanisław Ołdziej DNA binding to DnaA replication initiator protein – implications on the structure of the replication initiation complex |
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11.45-13.15 | session 26 Place: S204 | session 27 Place: S205 | session 28 Place: S207 | session 29 Place: S208 |
Jacek Drobnik MU, M Łódź, Poland Aleksander R. Sieroń SUM Katowice, Poland Biochemistry of the connective tissue | Jolanta Jura WBBB UJ, Cracow, Poland Piotr Widłak IO Gliwice, Poland Inflammation and cancer | Hanna Mazur-Marzec UG, Gdańsk, Poland Konrad Ocalewicz UG, Gdańsk, Poland Marine biotechnology | Janusz Rak UG, Gdańsk, Poland Elise Dumont ENS, Lyon, France Modeling of radiation damage to DNA |
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| Lectures: | Lectures: | Lectures: | Lectures: | |
11.45-12.15 | L.26.1. Leszek Kaczmarek Nencki Inst. of Experimental Biology PAS, Poland Matrix metalloproteinase-9 in the brain: Beyond the connective tissue | L.27.1. Wim Declercq VIB Center for Inflammation Research IRC, Belgium RIPK4 maintains epidermal homeostasis and prevents skin cancer by suppressing mitogenic signaling | L.28.1. Hanna Mazur-Marzec UG, Gdańsk, Poland Biotechnological potential of Baltic cyanobacteria. | L.29.1. Michael D. Sevilla Oakland University, MI, USA. Free radical mechanisms of radiation damage to DNA |
12.15-12.30 | L.26.2. Aleksander R. Sieroń SUM, Katowice, Poland Tolloids, function-structure relations and related disorders resulting from extra-cellular matrix pathology | O.27.1. Agata Lichawska-Cieslar Epidermal MCPIP1 function is essential to maintain proper skin homeostasis | L.28.2. Małgorzata Wiweger IIMCB, Warsaw, Poland Fish models for biomedical research. | L.29.2. Jorge Kohanoff Queen's University Belfast, UK Can low-energy electrons produce DNA strand breaks in the physiological environment? |
12.30-12.45 | O.27.2. Luiza Handschuh Levels of NPM1 alternative transcripts in acute myeloid and lymphoblastic leukemia |
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12.45-12.55 | O.26.1. Małgorzata Gałdyszyńska Collagen metabolism within cardiac fibroblast is modified by physical properties of cell environment | O.27.3. Seweryn Mroczek The non-canonical poly(A) polymerase FAM46C regulates B-cells proliferation and acts as an onco-suppressor in multiple myeloma | O.28.1. Ewa Piotrowska Characterization of biological activities of marine cyanobacteria-derived peptides | L.29.3. Elise Dumont ENS, Lyon, France Probing the mechanistic pathways and structural aftermaths of complex DNA lesions |
12.55-13.00 | O.26.2. Monika Dyńda Effect of the extracellular collagen type I on cardiac fibroblasts |
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13.00-13.05 | O.27.4. Piotr Widłak (Serum) cancer biomarkers or inflammation biomarkers? | O.28.2. Sławomir Ciesielski Marine bacteria as potential producers of polyhydroxyalkanoates |
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13.05-13.15 | O.26.3. Jacek Drobnik Effect of histamine on collagen content in cardiac myofibroblasts culture |
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13.15-13.20 | ||||
13.30-14.00 | Lunch andPoster session: P20-P31 Poster sessions list |
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14.00-14.45 | Closing Lecture Agnieszka Chacińska Centre of New Technologies University of Warsaw, Poland IRAP Warsaw Lecture Stress management in response to mitochondrial dysfunction Place: S205 |
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14.45-16.30 | Closing Ceremony Place: S205 |
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Tuesday, 18th September 2018 |
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15.00-17.30 | Meeting of the Board of Polish Biochemical Society Place: D209 |
18.00-19.30 | Opening ceremony Opening Lectures Place: S204/205 |
18.30-19.00 | PL.1. Ted Hupp University of Edinburgh, Scotland, International Centre for Cancer Vaccine Science Gdańsk Interferon responsive genes that link adaptive and innate immunity in human cancer Place: S204/205 |
19.00-19.30 | PL.2. Robin Fahraeus Paris Diderot University, France, International Centre for Cancer Vaccine Science Gdańsk Viral mRNA translation control: linking immune evasion with oncogenesis Place: S204/205 |
19.30 | Welcome Party Place: Upper level of the Faculty of Social Sciences University of Gdańsk |
Wednesday, 19th September 2018 |
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| Plenary Lecture | |||||
| Morning sessions 9.00-9.45 | PL.3. Marek Figlerowicz Institute of Bioorganic Chemistry PAS, Poznań, Poland Genomics in uncovering our history Place: S205 |
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| Session line | |||||
DNA World | RNA World | EMBO | Polish Society for Cell Biology |
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| session 1 Place: S204 | session 2 Place: S205 | session 3 Place: S207 | session 4 Place: S208 |
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| Morning sessions 9.45-13.15 | Marek Figlerowicz IBCh PAS, Poland Tomasz Żemojtel Berlin Inst. of Health, Germany Genomics and genomics-driven research | Andrzej Dziembowski IBB & UW, Poland RNA and RNP structures and mechanisms of action: from theory to experiment | Krzysztof Liberek IFB UG&MUG, Gdańsk, Poland Joanna Sułkowska CENT Poland EMBO Session | Halina Gabryś UJ, Cracow, Poland Signaling in plant cells |
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| Lectures: | Lectures: | Lectures: | Lectures: | ||
09.45-09.50 | IBCh PAS, Poland Tomasz Żemojtel Berlin Inst. of Health, Germany Short introduction | L.2.1. Marcin Nowotny IIMCB, Warsaw, Poland Structural and biochemical studies of the yeast mitochondrial RNA degradosome | Krzysztof Liberek IFB UG&MUG, Gdańsk, Poland Introduction | L.4.1. Ute Vothknecht Univ. of Bonn, Germany Calcium Regulation of Plant Organellar Metabolism |
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09.50-10.00 | L.3.1. Magda Konarska CENT, Warsaw, Poland, new EMBO member Dynamic rearrangements of the spliceosomal catalytic center |
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10.00-10.15 | L.1.1. Izabela Makałowska UAM, Poznań, Poland Activity of retroposed genes in tumors |
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10.15-10.30 | L.2.2. Jacek Jemielity CENT, Warsaw, Poland Chemically modified mRNA | L.3.2. Joanna Sułkowska CENTR, Warsaw, Poland EMBO Young Investigator Mysteries of entanglement – from a single protein to a pair of chromosomes | L.4.2. Axel Mithofer Max-Planck-Inst. for Chemical Ecology, Jena, Germany Plant Calcium Signaling in biotic Interactions |
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10.30-10.35 |
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10.35-10.40 | L.1.2. Tomasz Żemojtel Berlin Inst. of Health, Germany Liquid biopsy: challanges and opportunities |
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10.40-10.45 | L.3.3. Piotr Ziółkowski UAM, Poznań, Poland EMBO Installation Ggrantee Control of meiotic recombination: from chromosomal distribution to crossover frequency |
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10.45-11.05 | L.2.3. Maciej Kozak UAM, Poznań, Poland Applications of small-angle X-ray and neutron scattering (SAXS/SANS) in studies of complexes and flexible protein structures | L.4.3. Halina Gabryś UJ, Cracow, Poland Calcium and magnesium in blue light signaling in the mesophyll cell |
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11.05-11.10 | Break | ||||
11.10-11.15 | Break | ||||
11.15-11.35 | Break | ||||
11.35-11.40 | Break | L.3.4. Marta Miączyńska IIMCB, Warsaw, Poland new EMBO member Inflammatory signaling from the endocytic pathway | Break | ||
11.40-11.45 | L.1.3. Agnieszka Żmieńko AthCNV - a map of DNA copy number variations in Arabidopsis thaliana genome based on the 1001 Genomes Project data | Break | |||
11.45-12.00 | L.2.4. Krzysztof Ginalski CENT, Warsaw, Poland Identification and classification of proteins involved in nucleic acids metabolism | L.4.4. Dorota Konopka-Postupolska IBB, Warsaw, Poland The role of calcium in cellular membrane flow |
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12.00-12.15 | L.3.5. Maria Górna UW, Warsaw, Poland EMBO Installation Grantee Installation Grantee How to end a viral RNA- lessons from the IFIT proteins |
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12.15-12.25 | O.1.1. Małgorzata Marcinkowska-Swojak Half the costs keep the quality. Targeted enrichment for the Next Generation Sequencing of ancient genomes | L.2.5. Andrzej Dziembowski CENTIBB & UW, Warsaw, Poland Regulation of gene expression by non-canonical poly(A) and poly(U) polymerases | O.4.1.Małgorzata Pietrowska-Borek Is RAB GTPase homolog E1B (RABE1b) involved in response to cadmium stress in Arabidopsis thaliana seedlings by cGMP synthesis? |
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12.25-12.30 | L.3.6. Wojciech Pokrzywa IIMCB, Warsaw, Poland EMBO Installation grantee Chaperone-directed ubiquitylation maintains proteostasis at the expense of longevity |
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12.30-12.45 | O.1.2. Patrycja Jakubek Catechins as modulators of DNA methylation | O.4.2. Weronika Krzeszowiec-Jeleń Exogenous amino acids affect the image of actin cytoskeleton in Arabidopsis mesophyll cells |
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12.45-12.50 | O.1.3. Sabina Żołędowska Investigating the pangenome of the plant pathogenic Pectobacterium parmentieri provides insight into its outstanding adaptation abilities | O.2.1. Roman Szczęsny The mitochondrial degradosome complex and its co-factors prevent accumulation of double-stranded RNA in humans | |||
12.50-13.00 | L.3.7. Agata L. Starosta Undercover translation. Hidden secrets of the ribosome |
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13.00-13.15 | O.1.4. Agata Motyka Closure of the Dickeya solani pangenome | O.2.2. Michał Wojciech Szcześniak Long non-coding RNAs as modulators of splicing in trans via direct RNA:RNA interactions |
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13.30-14.15 | Lunch andPoster session: P1-P8 Poster sessions list |
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14.30-15.15 | PL.4. Bożena Kamińska-Kaczmarek Nencki Institute of Experimental Biology Polish Academy of Sciences, Warsaw, Poland Immune microenvironment of glioma Lecture sponsored by Nencki Inst. of Experimental Biology PAS, Warsaw, Poland- 100 years anniversary of the Nencki Inst. of Experimental Biology PAS Place: S205 |
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| Session line | |||||
New molecular targets / World of application | RNA World | Protein World | Session sponsored by COST Action CA16112 "NutRedOx" |
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| session 5 Place: S204 | session 6 Place: S205 | session 7 Place: S207 | session 8 Place: S208 | session 30 Place: S211 |
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| Afternoon sessions 15.15-16.45 | Krystyna Bieńkowska-Szewczyk IFB UG&MUG, Gdańsk, Poland Bogusław Szewczyk UG&MUG Molecular virology | Zofia Szweykowska-Kulińska UAM, Poznań, Poland Piotr Kozłowski IBCh PAS, Poznań, Poland Non-coding RNA and gene expression | Marcin Nowotny IIMCB, Warsaw, Poland Alessandro Costa The Francis Crick Inst., London, UK Structural studies of large assemblie | Adam Szewczyk Nencki Inst. of Experimental Biology PAS, Warsaw, Poland Wiesława Jarmuszkiewicz UAM, Poznań, Poland Molecular bioenergetics | Caroline Gaucher University of Lorraine, Nancy, France Jędrzej Antosiewicz MUG, Gdańsk, Poland Redox control of major age-related diseases |
| Lectures: | Lectures: | Lectures: | Lectures: | Lectures: | |
15.15-15.25 | L.5.1. Timm C. Harder FLI, Riems, Germany 100 years from Spanish flu- can we control influenza today? | Zofia Szweykowska-Kulińska UAM, Poznań, Poland Piotr Kozłowski IBCh PAS, Poznań, Poland Marek Figlerowicz Institute of Bioorganic Chemistry PAS, Poznań, Poland Introduction In memory of Professor Włodzimierz Krzyżosiak | L.7.1. Wojciech Galej EMBL, Grenoble, France Structure and dynamics of the spliceosome | L.8.1. Wiesława Jarmuszkiewicz UAM, Poland Impact of temperature and training on skeletal muscle bioenergetics | L.30.1. Marc Diederich Seoul National University, Korea About canonical and less canonical cell death induction by natural compounds with pharmacological potential |
15.25-15.45 | L.6.1. Zofia Szweykowska-Kulińska UAM, Poland Biogenesis and function of plant microRNAs |
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15.45-16.05 | L.5.2. Arvind H. Patel MRC-University of Glasgow Centre for Virus Research, UK Conformational flexibility in the receptor-binding site of the Hepatitis C Virus Glycoprotein E2 100 years from Spanish flu- can we control influenza today? | L.6.2. Piotr Kozłowski IBCh PAS, Poznań, Poland Copy number variation and other types of genetic alterations in miRNA genes and their potential implications for miRNA function and human diseases | L.7.2. Alessandro Costa The Francis Crick Institute, London, UK Eukaryotic replisome assembly and fork progression visualized by cryo-EM | L.8.2. Wiesław Gruszecki UMCS, Lublin, Poland Warming-up of the chloroplast | L.30.2. Marek Naruszewicz Medical University of Warsaw, Poland Oleacein, translation from Mediterranean diet to preventive medicine |
16.05-16.15 | O.6.1. Susheel Sagar Bhat Arabidopsis thaliana mRNA adenosine methylase (MTA) is an important player in miRNA biogenesis regulatory pathway |
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16.15-16.25 | L.5.3. Alicja Chmielewska Adenovirus vectors for genetic vaccination and oncolytic virotherapy | O.6.2. Anna Kurzyńska-Kokorniak A possible direct involvement of Dicer ribonuclease in the post-transcriptional control of gene expression | L.7.3.Michał Szymański IFB UG & GUMed, Gdańsk, Poland Structure and function of macromolecular machines | L.8.3. Adam Szewczyk Nencki Inst. of Experimental Biology PAS, Warsaw, Poland Mitochondrial regulation of mitochondrial potassium channels | L.30.3. Tomris Ozben Natural redox modulators of oxidative stress and chemoresistance in cancer therapy: beneficial versus deleterious effects |
16.25-16.35 | O.6.3. Joanna Boguslawska TGF-β1 affects proliferation, viability and migration of renal cancer cells, possibly by targeting regulatory microRNAs |
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16.35-16.45 | O.6.4. Ankur Gadgil U7 snRNA activity and histone gene expression is affected by ALS-linked FUS mutations |
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16.45-17.00 | Break | Break | |||
17.00-18.00 | Sponsored session Place: S205 | O.8.1. Bogusz Kulawiak Single-channel properties of the ROMK2-pore-forming subunit of the mitochondrial ATP-regulated potassium channel |
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17.00-17.15 | Merck sponsored session Immunophenotyping Extracellular Vesicles using innovative flow cytometry |
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17.15-17.30 | O.7.1. Michał Gabruk Towards the near-atomic resolution structure of light-dependent protochlorophyllide oxidoreductase | O.8.2. Andonis Karachitos Evaluation of mitochondrial energetic status and oxidative stress during tardigrade anhydrobiosis |
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17.30-17.45 | O.8.3. Karol Parchem Dietary oxidized phospholipids: digestion, absorption and metabolism |
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17.45-17.55 | O.8.4. Karolina Dominiak Coenzyme Q and ROS production in mitochondria |
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17.55-18.00 |
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18.00-19.30 | General assembly of the Polish Biochemical Society Place: S205 |
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Thursday, 20th September 2018 |
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| Plenary Lecture | |||||
| Morning session 9.00-9.45 | PL.5. Peter Mackenzie Flinders University, Adelaide, Australia The UDP glycosyltransferase superfamily: its role in signal transduction termination and protection against chemical toxicity Lecture sponsored by the Rector of the Gdańsk University of Technology Place: S205 |
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| Session line | |||||
Metabolite World | Cell & Organ World | DNA World | Sesion sponsored by COST Action CA16112 "NutRedOx" |
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9.45-11.15 | session 9 Place: S204 | session 10 Place: S205 | session 11 - part I Place: S207 | session 12 Place: S208 | session 30 part II Place: S211 |
Władysława A. Daniel PAS, Poland Krzysztof Safranow PUM, Szczecin, Poland The physiological and pharmacological regulation of endobiotic and drug metabolizing enzymes | Ryszard T. Smoleński MUG, Gdańsk, Poland Stefan Chłopicki UJ, Cracow, Poland Endothelial dysfunction and atherosclerosis | Agnieszka Łoboda UJ, Cracow, Poland Robert Passier University of Twente, Enschede, The Netherlands Medical biotechnology in regenerative medicine and drug research Session sponsored by STARBIOS 2 Structural Transformation to Attain Responsible BIOSciences EU FP Horizon 2020 | Jarosław Marszałek IFB UG&MUG, Gdańsk, Poland Ryszard Korona UJ, Cracow, Poland Evolutionary biochemistry | Agnieszka Bartoszek Gdańsk University of Technology, Gdańsk Mustafa C. Malki Université de Bourgogne, Dijon, France Redox control of major age-related diseases |
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| Lectures: | Lectures: | Lectures: | Lectures: | Lectures: | |
09.45-10.15 | L.9.1. Władysława A. Daniel PAS, Poland The regulation of liver cytochrome P450 by the brain nervous system | L.10.1. Ryszard T. Smoleński MUG, Gdańsk, Poland Energetics of cardiac myocyte in atherosclerosis | L.11.1. Graziella Pellegrini Univ. of Modena, Italy Epithelial stem cells, a real tool for effective regenerative medicine treatments | L.12.1. Grzegorz Kudła Univ. of Edinburgh, UK Next generation genotype-phenotype mapping | L.30.4. Linda Giblin Whey Protein: can it boost cellular antioxidant processes? |
10.15-10.45 | L.9.2. Krzysztof Safranow PUM, Szczecin, Poland Consequences of muscle AMP deaminase deficiency caused by common nonsense mutation In AMPD1 gene – a new look at the role of purine nucleotide cycle | L.10.2. Stefan Chłopicki UJ, Cracow, Poland Endothelial profiling in vivo: novel approach to experimental pharmacology of endothelium | L.11.2. Józef Dulak UJ, Cracow, Poland Targeting inflammation for treatment of Duchenne muscular dystrophy | L.12.2. Kataryna Tomala UJ, Cracow, Poland Searching for factors underlaying slower evolution of abundant proteins | L.30.5. Jarosław Paluszczak Modulation of Wnt signaling by natural and synthetic compounds in cancer cells |
10.45-11.00 | O.9.1. Agnieszka Potęga Electrochemistry/liquid chromatography/mass spectrometry for the simulation of in vitro metabolism of unsymmetrical bis-acridines with antitumor properties | O.10.1. Alicja Bulińska Nucleotide and adenosine converting ecto-enzyme pattern in endothelial activation and vascular inflammation | O.11.1. Krzysztof Kobielak Regulation of hair follicle stem cells homeostasis by activation of gene inhibitory network | L.12.3. Ryszard Korona UJ, Cracow, Poland The paradox of dominance: halving the dose of a gene leaves its function unaffected (usually) | |
11.00-11.15 | O.10.2. Armen Trchounian Antioxidant activity of alcohol extracts from some plants of Armenian flora: the highest level and its possible nature | O.11.2. Jacek Stępniewski Administration of HO-1/SDF-1α-overexpressing mesenchymal stromal cells in murine and swine model of myocardial infarction and heart failure – analysis of therapeutic effect |
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11.15-11.45 | Break | ||||
| Session line | |||||
Metabolite World | Cell & Organ World | New molecular targets / World of application |
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11.45-13.15 | session 13 Place: S204 | session 14 Place: S205 | session 11 - part II Place: S207 | session 15 Place: S208 |
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Wanda Baer-Dubowska PUMS, Poland Gniewomir Latacz UJ, Cracow, Poland Metabolic activation of xenobiotics - therapeutic target and drug monitoring | Anna Ronowska Medical University of Gdańsk, Poland Andrzej Szutowicz Medical University of Gdańsk, Poland New biomarkers in neurodegenerative diseases | Józef Dulak UJ, Cracow, Poland Graziella Pellegrini University of Modena, Modena, Italy Medical biotechnology in regenerative medicine and drug research Session sponsored by STARBIOS 2 Structural Transformation to Attain Responsible BIOSciences EU FP Horizon 2020 | Tomasz Wilanowski Nencki Inst. of Experimental Biology PAS, Warsaw, Poland Anna Radominska-Pandya University of Arkansas of Medical Sciences , USA New molecular targets in personalized therapy of cancer |
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| Lectures: | Lectures: | Lectures: | Lectures: | ||
11.45-12.15 | L.13.1. Uwe Sauer Inst. of Molecular Systems Biology, Switzerland Metabolic coordination through metabolite-protein interactions | L14.1. Monika Szeliga-Mossakowski Medical Research Centre PAS, Warsaw, Poland Astroglia in health and pathology | L.11.3. Robert Passier Univ. of Twente, The Netherlands Human pluripotent stem cell-derived cardiac cells for disease modeling, drug screening and regenerative medicine | L.15.1. Tomas Wilanowski Nencki Inst. of Experimental Biology PAS, Warsaw, Poland Grainyhead-like transcription factors as targets of anti-cancer therapy |
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12.15-12.45 | L.13.2. Hanna Piotrowska-Kempisty PUMS, Poland The metabolic activation of methylated resveratrol analogue 3,4,4’,5-tetra-methoxystilbene (DMU-212) to 3’hydroxy-3,4,4,4’-tetramethoxystilbene (DMU-214) | L.14.2. Andrzej Szutowicz MUG, Gdańsk, Poland Regulatory effects of acetyl-CoA distribution in cellular compartments of healthy and diseased brain | L.11.4. Agnieszka Łoboda UJ, Cracow, Poland HO-1 as a possible drug target | L.15.2. Anna Radominska-Pandya UAMS, USA Natural Compounds Activating Cannabinoid Receptors CB1 and CB2: future for the cancer treatments |
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12.45-12.55 | O.13.1. Mikhail Kurbat Hyperhomocysteinemia caused by highly active antiretroviral therapy (HAART) of HIV infection: focus on mitochondria | O.14.1. Anna Ronowska Thiamine deficits aggravate zinc cytotoxicity in cholinergic SN56 neuronal cells | O.11.3. Katarzyna Kaławaj Alpha-ketoglutarate (AKG) induces apoptosis in osteosarcoma cells in vitro through the activation of JNK MAP kinase | O.15.1. Małgorzata Rogalińska The importance of drug type and dose on CLL cells in vitro sensitivity to anticancer-agents |
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12.55-13.00 | O.15.2. Łukasz Skalniak Novel strategies of PD-1/PD-L1 immune checkpoint blockade for cancer therapy: antibodies, peptides and small molecule |
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13.00-13.05 | O.13.2. Annamaria Lubelska Metabolic stability as a challenge in the early stage of drug discovery process – in vitro determination of metabolic pathways for new promising 5-HT7R ligands | O.11.4. Izabela Sadowska-Bartosz 3-Bromopyruvic acid: a small molecule with strong anti-tumor potency |
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13.05-13.15 | O.15.3. Błażej Rubiś Telomerase targeting modulates cancer response to therapy |
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13.30-14.15 | Lunch andPoster session: P11-P19 Poster sessions list |
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14.30-15.15 | PL.6. Narayanan Veeraraghavan Rady Children’s Hospital-San Diego, USA Clinical Utility of Rapid Whole Genome Sequencing in pediatric critical care Lecture sponsored by Rector of the Medical University of Gdańsk Place: S205 |
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| Session line | |||||
Metabolite World | Cell & Organ World | New molecular targets / World of application | Satellite session: Women in Science |
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15.15-16.45 | session 16 Place: S204 | session 17 Place: S205 | session 18 Place: S207 | session 19 Place: S208 | Satellite session 1 Place: S211 |
Micał Markuszewski MUG, Gdańsk, Poland Micał Ciborowski Medical University of Bialystok Clinical metabolomics | Rafał Sądej IFB UG&MUG, Poland Anna Żaczek IFB UG&MUG, Poland Tumor microenvironment in cancer progression | Piotr Trzonkowski MUG, Poland Ewa M. Martinez-Caceres Generalitat de Catalunya, Spain New molecular targets in personalized therapy of autoimmune diseases Session sponsoring by - COST project - Action to Focus and Accelerate Cell-based Tolerance-inducing Therapies BM1305, EU FP Horizon 2020. | Hanna Jańska UWr, Wrocław, Poland Agnieszka Mostowska UW, Warsaw, Poland Inside plant organelles: structure, function and stress response | Session sponsored by L’Oreal Poland Chairwoman - Agnieszka Chacińska Centre of New Technologies University of Warsaw, Poland |
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| Lectures: | Lectures: | Lectures: | Lectures: | Lectures: | |
15.15-15.45 | L.16.1. Danuta Dudzik San Pablo CEU University, Madrid, Spain Metabolomics meets clinics - application to maternal-fetal and neonatal medicine | L.17.1. Przemysław Juszczyński IHiTM, Poland Tumor suppressor function of FOXO1 in diffuse large B-cell lymphomas: mechanisms of regulation and rational targeting strategies Parnas Memory Lecture | L.18.1. Ewa M. Martinez-Caceres Generalitat de Catalunya, Spain Tolerance-induction with autologous tolerogenic dendritic cells treated with VITamin D3 and loaded with myelin peptides in MultiPe Sclerosis (Tolervit-MS) | L.19.1. Oliver van Aken Lund Univ., Sweden Exploring organelle-to-nuclear signaling during plant stress responses. | Annie Black Deputy Executive Director L'Oréal Corporate Foundation, France Introduction Agnieszka Chacińska Centre of New Technologies University of Warsaw, Poland Panelists: Bożena Kamińska Nencki Institute of Experimental Biology Polish Academy of Sciences, Warsaw, Poland Agata Starosta Maria Curie Skłodowska University in Lublin, Poland Joanna Sułkowska Centre of New Technologies University of Warsaw, Poland Zofia Szweykowska-Kulińska Adam Mickiewicz University Poznań, Poland |
15.45-16.15 | L.16.2. Michał Ciborowski Medical University of Bialystok, Poland Metabolomics in the clinical settings. Applications in diabetology and endocrinology | L.17.2. Katarzyna Miękus UJ, Cracow, Poland Role of anti-inflammatory protein MCPIP1 in clear cell renal cell carcinoma progression | L.18.2. Piotr Trzonkowski MUG, Gdańsk, Poland T-regulatory cells to treat autoimmune diseases | L.19.2. Łucja Kowalewska UW, Warsaw, Poland Structural plasticity of the chloroplast thylakoid network. |
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16.15-16.45 | L.17.3. Rafał Sądej IFB UG&MUG, Gdańsk, Poland Tumour microenvironment in luminal breast cancer progression | L.19.3. Małgorzata Heidorn-Czarna UW, Warsaw, Poland Functional relevance of mitoproteases in plant mitochondria. |
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16.45-17.00 | Break | ||||
17.00-18.30 | session 20 Place: S204 | session 17 continued Place: S205 | session 21 Place: S207 | session 22 Place: S208 |
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Ewa Świeżewska IBB, Warsaw, Poland Anna Ihnatowicz IFB UG&MUG, Gdańsk, Poland Plant biochemistry and metabolomics | Rafał Sądej IFB UG&MUG, Poland Anna Żaczek IFB UG&MUG, Poland Tumor microenvironment in cancer progression | Marta Olejniczak IBCh PAS, Poznań, Poland Krzysztof Chyliński CRISPR Lab, Wien, Austria CRISPR technologies for targeted genome editing | Dariusz Rakus UWr, Wrocław, Poland Jacek R. Wiśniewski MPI Biochemie, Germany Proteomics of ageing and diseases |
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| Lectures: | Oral presentations | Lectures: | Lectures: | ||
17.00-17.20 | L.20.1. Asaph Aharoni Weizmann Inst., Israel Plant ‘Metabolic Caravans’: from anti-nutritional to anti-Parkinson alkaloids | O.17.1. Halina Waś Chemotherapeutics-treated cancer cells display stem-like and senescent cell feature | L.21.1. Krzysztof Chyliński CRISPR Lab Vienna, Austria Temporal control of CRISPR/Cas9 activity | L.22.1. Jacek R. Wiśniewski MPI Biochemie, Germany Large scale proteomics for studying physiology and disease |
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17.20-17.30 | |||||
17.30-17.40 | L.20.2. Anna Ihnatowicz IFB UG&MUG, Gdańsk, Poland Genetic regulation of isoprenoid accumulation in plants – what have we learned from analysis of biochemical and genetic data? | L.21.2. Marta Olejniczak IBCh PAS, Poznań, Poland Evaluation of CRISPR/Cas9-mediated genome editing efficiency | L.22.2. Aneta Stachowicz Proteomics of plasma fibrin clot in antiphospholipid syndrome |
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17.40-17.55 | O.17.2. Natalia Bednarz-Knoll Preoperative high platelets counts and low hemoglobin correlate to mesenchymal phenotype of circulating tumor cells and worse clinical outcome in human breast carcinoma |
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17.55-18.00 | O.17.3. Aleksandra Solecka The influence of metabolism on the phenotype of astrocytoma U-251 MG cell line |
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18.00-18.10 | O.20.1. Joanna Grzyb Bionanohybrids between phycobilisomes and colloidal quantum dots – studies of energy transfer in complicated systems | L.22.3. Dariusz Rakus UWr, Wrocław, PolandAging-associated changes in hippocampal glycogen metabolism. Evidence for and against astrocyte-neuron lactate shuttle |
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18.10-18.15 | O.17.4. Izabela Papiewska-Pająk Extracellular vesicles secreted by colorectal cancer cell line HT29 overexpressing Snail can fuse with and activate the cells constituting metastatic niche |
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18.15-18.25 | O.20.2. Katarzyna Jasieniecka-Gazarkiewicz Acyl-CoA:lysophosphatidylethanolamine acyltransferase (LPEAT) activity regulates plant growth and autophagy level |
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18.25-18.30 | O.17.5. Magdalena Mizerska-Kowalska Tumor-associated neutral endopeptidase (tNEP) regulates cell proliferation and TGF-β production in cultures and co-cultures of colon cancer cells with colon fibroblasts |
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18.30-18.40 | |||||
20.00 | Gala Dinner including complimentary lecture Place: UNICORN Restaurant |
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Friday, 21st September 2018 |
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| Plenary lecture | ||||
9.00-9.45 | PL.7. Magdalena Król SGGW, Warsaw, Poland The macrophage-drug conjugate (MDC) as a „Trojan horse” approach in cancer therapy Polish Biochemical Society & L’Oreal for Women in Science Honorary Lecture Place: S205 |
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Metabolite World | Cell & Organ World | World of Application / Bioinformatics |
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9.45-11.15 | session 23 Place: S204 | session 24 Place: S205 | session 25 Place: S207 |
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Joanna Sułkowska CENT, Warsaw, Poland Andrzej Joachimiak Argonne National Laboratory, Argonne, USA Entanglement in biology - from proteins folding to drug design | Grzegorz Węgrzyn UG, Gdańsk, Poland Ewa Bartnik UW, Warsaw, Poland Mitochondrial and lysosomal diseases | Cezary Czaplewski UG, Gdańsk, Poland Stanisław Ołdziej IFB UG&MUG, Gdańsk, Poland From experimental data to in silico simulations and way back Session sponsored by Openexome |
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9.45-10.15 | L.23.1. Andrzej Joachimiak Argonne National Laboratory, Argonne, USA Targeting allosteric site in drug discovery – a case of tryptophan synthase | L.24.1. Grzegorz Węgrzyn UG, Gdańsk, Poland Mechanisms and therapeutic options of lysosomal storage diseases | L.25.1. Pavel Jungwirth Inst. Organic Chemistry and Biochemistry, ASCz, Prague, Czech Rep. Cell Penetration and Membrane Fusion: Two Sides of the Same Coin Lecture Sponsored by the Rector of the University of Gdańsk |
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10.15-10.45 | L.23.2. Ya-Ming Hou Thomas Jefferson University, Philadelphia, USA tRNA methylation: a determinant of mitochondrial pathogenesis | L.24.2. Ewa Bartnik UW, Wrocław, Poland Leber's hereditary optic neuropathy | L.25.2. Cezary Czaplewski UG, Gdańsk, Poland Modeling of protein structure and dynamics with the UNRES force field assisted by limited experimental data and knowledge-based information |
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10.45-11.00 | O.23.1. Rafal Augustyniak Visualizing supramolecular machines in action by methyl TROSY-NMR - substrate processing by AAA+ unfoldases | O.24.1. Katarzyna Tońska Nuclear genes involved in mitochondrial diseases with mitochondrial DNA instability in adults | O.25.1. Piotr Setny Protein hydraulics: water driven substrate binding cooperativity to protein kinase A |
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11.00-11.15 | O.23.2. Agata Perlinska Characterization of substrate binding and function of a knotted protein | O.24.2. Marta Kaczor-Kamińska The murine cellular model of mucopolysaccharidosis III, type B (MPS IIIB) – a preliminary study | O.25.2. Stanisław Ołdziej DNA binding to DnaA replication initiator protein – implications on the structure of the replication initiation complex |
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11.45-13.15 | session 26 Place: S204 | session 27 Place: S205 | session 28 Place: S207 | session 29 Place: S208 |
Jacek Drobnik MU, M Łódź, Poland Aleksander R. Sieroń SUM Katowice, Poland Biochemistry of the connective tissue | Jolanta Jura WBBB UJ, Cracow, Poland Piotr Widłak IO Gliwice, Poland Inflammation and cancer | Hanna Mazur-Marzec UG, Gdańsk, Poland Konrad Ocalewicz UG, Gdańsk, Poland Marine biotechnology | Janusz Rak UG, Gdańsk, Poland Elise Dumont ENS, Lyon, France Modeling of radiation damage to DNA |
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11.45-12.15 | L.26.1. Leszek Kaczmarek Nencki Inst. of Experimental Biology PAS, Poland Matrix metalloproteinase-9 in the brain: Beyond the connective tissue | L.27.1. Wim Declercq VIB Center for Inflammation Research IRC, Belgium RIPK4 maintains epidermal homeostasis and prevents skin cancer by suppressing mitogenic signaling | L.28.1. Hanna Mazur-Marzec UG, Gdańsk, Poland Biotechnological potential of Baltic cyanobacteria. | L.29.1. Michael D. Sevilla Oakland University, MI, USA. Free radical mechanisms of radiation damage to DNA |
12.15-12.30 | L.26.2. Aleksander R. Sieroń SUM, Katowice, Poland Tolloids, function-structure relations and related disorders resulting from extra-cellular matrix pathology | O.27.1. Agata Lichawska-Cieslar Epidermal MCPIP1 function is essential to maintain proper skin homeostasis | L.28.2. Małgorzata Wiweger IIMCB, Warsaw, Poland Fish models for biomedical research. | L.29.2. Jorge Kohanoff Queen's University Belfast, UK Can low-energy electrons produce DNA strand breaks in the physiological environment? |
12.30-12.45 | O.27.2. Luiza Handschuh Levels of NPM1 alternative transcripts in acute myeloid and lymphoblastic leukemia |
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12.45-12.55 | O.26.1. Małgorzata Gałdyszyńska Collagen metabolism within cardiac fibroblast is modified by physical properties of cell environment | O.27.3. Seweryn Mroczek The non-canonical poly(A) polymerase FAM46C regulates B-cells proliferation and acts as an onco-suppressor in multiple myeloma | O.28.1. Ewa Piotrowska Characterization of biological activities of marine cyanobacteria-derived peptides | L.29.3. Elise Dumont ENS, Lyon, France Probing the mechanistic pathways and structural aftermaths of complex DNA lesions |
12.55-13.00 | O.26.2. Monika Dyńda Effect of the extracellular collagen type I on cardiac fibroblasts |
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13.00-13.05 | O.27.4. Piotr Widłak (Serum) cancer biomarkers or inflammation biomarkers? | O.28.2. Sławomir Ciesielski Marine bacteria as potential producers of polyhydroxyalkanoates |
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13.05-13.15 | O.26.3. Jacek Drobnik Effect of histamine on collagen content in cardiac myofibroblasts culture |
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13.15-13.20 | ||||
13.30-14.00 | Lunch andPoster session: P20-P31 Poster sessions list |
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14.00-14.45 | Closing Lecture Agnieszka Chacińska Centre of New Technologies University of Warsaw, Poland IRAP Warsaw Lecture Stress management in response to mitochondrial dysfunction Place: S205 |
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14.45-16.30 | Closing Ceremony Place: S205 |
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(The 3rd Congress of Polish Biosciences "BIO 2018 - Through interdisciplinary approach into new solutions” and 51st Meeting of the Polish Biochemical Society Gdańsk (Poland), 18-21 September 2018) - zadanie finansowane w ramach umowy 504/P-DUN/2018 ze środków Ministra Nauki i Szkolnictwa Wyższego przeznaczonych na działalność upowszechniającą naukę.